Clinical Features of Scrub Typhus

Regardless, these publications highlight the variable clinical presentation of scrub typhus and the importance of considering scrub typhus as part of the differential diagnosis for patients with nonspecific febrile illnesses in areas in which scrub typus is endemic. Laboratory diagnosis is mainly reliant on serological tests that are not widely available in regions of endemicity and that have suboptimal sensitivity and specificity, especially when only acute-phase serum samples are available for testing.