A New Total Synthesis of Porritoxin
A concise and efficient total synthesis of the phytotoxin porritoxin is described. The key step of the synthesis is based upon a Parham cyclization methodology which enables the creation of the lactam unit embedded in the title compound framework with the concomitant formation of the tethered hydrox...
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| Veröffentlicht in: | Journal of organic chemistry 2006-04, Vol.71 (8), p.3303-3305 |
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| container_end_page | 3305 |
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| container_issue | 8 |
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| container_title | Journal of organic chemistry |
| container_volume | 71 |
| creator | Moreau, Anne Lorion, Magali Couture, Axel Deniau, Eric Grandclaudon, Pierre |
| description | A concise and efficient total synthesis of the phytotoxin porritoxin is described. The key step of the synthesis is based upon a Parham cyclization methodology which enables the creation of the lactam unit embedded in the title compound framework with the concomitant formation of the tethered hydroxyakyl chain. |
| doi_str_mv | 10.1021/jo052592f |
| format | Article |
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The key step of the synthesis is based upon a Parham cyclization methodology which enables the creation of the lactam unit embedded in the title compound framework with the concomitant formation of the tethered hydroxyakyl chain.</description><identifier>ISSN: 0022-3263</identifier><identifier>EISSN: 1520-6904</identifier><identifier>DOI: 10.1021/jo052592f</identifier><identifier>PMID: 16599636</identifier><identifier>CODEN: JOCEAH</identifier><language>eng</language><publisher>Washington, DC: American Chemical Society</publisher><subject>Chemistry ; Exact sciences and technology ; Heterocyclic compounds ; Heterocyclic compounds with only one n hetero atom and condensed derivatives ; Indoles - chemical synthesis ; Indoles - chemistry ; Isoindoles ; Molecular Structure ; Organic chemistry ; Preparations and properties</subject><ispartof>Journal of organic chemistry, 2006-04, Vol.71 (8), p.3303-3305</ispartof><rights>Copyright © 2006 American Chemical Society</rights><rights>2007 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a381t-a0a6a2304e70b6b23307aea634ad17b7dec77faf1e89f183ff599b74600759653</citedby><cites>FETCH-LOGICAL-a381t-a0a6a2304e70b6b23307aea634ad17b7dec77faf1e89f183ff599b74600759653</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/jo052592f$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/jo052592f$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>314,780,784,2765,27076,27924,27925,56738,56788</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17747026$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16599636$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Moreau, Anne</creatorcontrib><creatorcontrib>Lorion, Magali</creatorcontrib><creatorcontrib>Couture, Axel</creatorcontrib><creatorcontrib>Deniau, Eric</creatorcontrib><creatorcontrib>Grandclaudon, Pierre</creatorcontrib><title>A New Total Synthesis of Porritoxin</title><title>Journal of organic chemistry</title><addtitle>J. Org. Chem</addtitle><description>A concise and efficient total synthesis of the phytotoxin porritoxin is described. 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| ispartof | Journal of organic chemistry, 2006-04, Vol.71 (8), p.3303-3305 |
| issn | 0022-3263 1520-6904 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_67838494 |
| source | MEDLINE; American Chemical Society Journals |
| subjects | Chemistry Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with only one n hetero atom and condensed derivatives Indoles - chemical synthesis Indoles - chemistry Isoindoles Molecular Structure Organic chemistry Preparations and properties |
| title | A New Total Synthesis of Porritoxin |
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