Recurrent IgA nephropathy after renal transplantation despite immunosuppressive regimens with mycophenolate mofetil

Background. Transplantation offers an excellent option for patients with immunoglobulin-A nephropathy (IgAN) with severe renal dysfunction. However, IgAN frequently recurs in allografts treated with azathioprine. We examined the impact of mycophenolate mofetil immunosuppression on recurrence of IgAN...

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Veröffentlicht in:Nephrology, dialysis, transplantation dialysis, transplantation, 2005-06, Vol.20 (6), p.1214-1221
Hauptverfasser: Chandrakantan, Arun, Ratanapanichkich, Piti, Said, Mowaffaq, Barker, Catherine V., Julian, Bruce A.
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Sprache:eng
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Zusammenfassung:Background. Transplantation offers an excellent option for patients with immunoglobulin-A nephropathy (IgAN) with severe renal dysfunction. However, IgAN frequently recurs in allografts treated with azathioprine. We examined the impact of mycophenolate mofetil immunosuppression on recurrence of IgAN. Methods. We reviewed the charts of patients transplanted for IgAN at our institution in the cyclosporin era. Patients were excluded from further analysis if follow-up was
ISSN:0931-0509
1460-2385
DOI:10.1093/ndt/gfh773