Measurement of free thyroxine concentration in horses by equilibrium dialysis

The purpose of the study reported here was to validate measurement of free thyroxine (fT4) concentration in equine serum by equilibrium dialysis (fT4D), and to compare values with fT4 concentration measured directly and with total T4 (TT4) concentration. The fT4D, fT74, and TT4 concentrations were m...

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Veröffentlicht in:	Journal of veterinary internal medicine 2006-03, Vol.20 (2), p.371-376
Hauptverfasser:	Breuhaus, B.A, Refsal, K.R, Beyerlein, S.L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Assay validation assays Dialysis - methods Dialysis - veterinary disease course Equilibrium dialysis Female Free thyroxine Horse Horse Diseases - blood Horse Diseases - diagnosis horses Horses - blood hypothyroidism Hypothyroidism - blood Hypothyroidism - diagnosis Hypothyroidism - veterinary L-thyroxine Male Nonthyroidal illness syndrome normal values Reference Values Thyroxine - blood validity
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Zusammenfassung:	The purpose of the study reported here was to validate measurement of free thyroxine (fT4) concentration in equine serum by equilibrium dialysis (fT4D), and to compare values with fT4 concentration measured directly and with total T4 (TT4) concentration. The fT4D, fT74, and TT4 concentrations were measured over a range of values in euthyroid horses and horses made hypothyroid by administration of propylthiouracil (PTU). Concentrations of fT4D (
ISSN:	0891-6640 1939-1676
DOI:	10.1111/j.1939-1676.2006.tb02870.x