Developmental Expression of NPY/PYY Receptors zYb and zYc in Zebrafish

: This study describes the developmental expression of zYb and zYc receptors in zebrafish. RT‐PCR demonstrated that both mRNAs are present from 24‐hour postfertilization (hpf) and that their expression increased during larval development. Whole‐mount in situ hybridization showed zYb mRNA expression in the epithalamus (24 hpf), telencephalon, hypothalamus, rhombencephalon (24‐96 hpf), mesencephalon (48‐96 hpf), hatching gland, and otic vesicle (48‐64 hpf). zYc mRNA is expressed in the epithalamus (24 and 96 hpf), telencephalon (48‐96 hpf), spinal cord, notochord (64 hpf), and hatching gland (96 hpf). These results show that zYb and zYc receptors are expressed during ontogeny, suggesting a role for neuropeptide Y (NPY) and/or peptide YY (PYY) in organogenesis.