Context-dependent codon bias and messenger RNA longevity in the yeast transcriptome

Context-dependent codon bias and messenger RNA longevity in the yeast transcriptome

Context-dependent codon bias and its relationship with messenger RNA (mRNA) longevity was examined in 4,648 mRNA transcripts of the Saccharomyces cerevisiae transcriptome for which mRNA half-lives have been empirically determined. Surprisingly, rare codon usage (codons used

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Veröffentlicht in:Molecular biology and evolution 2005-06, Vol.22 (6), p.1403-1411
1. Verfasser: Carlini, David B
Format: Artikel
Sprache:eng
Schlagworte:
Codon
Computational Biology - methods
Databases, Genetic
Genome, Fungal
Models, Genetic
Models, Statistical
Models, Theoretical
Open Reading Frames
Proteome
RNA - chemistry
RNA - genetics
RNA, Messenger - metabolism
Saccharomyces cerevisiae
Saccharomyces cerevisiae - genetics
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Zusammenfassung:Context-dependent codon bias and its relationship with messenger RNA (mRNA) longevity was examined in 4,648 mRNA transcripts of the Saccharomyces cerevisiae transcriptome for which mRNA half-lives have been empirically determined. Surprisingly, rare codon usage (codons used
ISSN:0737-4038
DOI:10.1093/molbev/msi135