Haloxylines A and B, Antifungal and Cholinesterase Inhibiting Piperidine Alkaloids from Haloxylon salicornicum

Haloxylines A (1) and B (2), new piperidine alkaloids, have been isolated from the chloroform soluble fraction of Haloxylon salicornicum and their structures elucidated by spectroscopic techniques including 2D-NMR. Both the compounds displayed antifungal and cholinesterase enzymes inhibitory potenti...

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Veröffentlicht in:	Chemical & Pharmaceutical Bulletin 2005, Vol.53(5), pp.570-572
Hauptverfasser:	Ferheen, Sadia, Ahmed, Ejaz, Afza, Nighat, Malik, Abdul, Shah, Muhammad Raza, Nawaz, Sarfraz Ahmad, Choudhary, Muhammad Iqbal
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholinesterase - metabolism Alkaloids - chemistry Alkaloids - isolation & purification Alkaloids - pharmacology Amaranthaceae antifungal activity Antifungal Agents - chemistry Antifungal Agents - isolation & purification Antifungal Agents - pharmacology Candida albicans - drug effects cholinesterase inhibition Cholinesterase Inhibitors - chemistry Cholinesterase Inhibitors - isolation & purification Cholinesterase Inhibitors - pharmacology haloxyline A haloxyline B Haloxylon salicornicum piperidine alkaloid Piperidines - chemistry Piperidines - isolation & purification Piperidines - pharmacology Plant Extracts - chemistry Plant Extracts - isolation & purification Plant Extracts - pharmacology Plant Structures
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Zusammenfassung:	Haloxylines A (1) and B (2), new piperidine alkaloids, have been isolated from the chloroform soluble fraction of Haloxylon salicornicum and their structures elucidated by spectroscopic techniques including 2D-NMR. Both the compounds displayed antifungal and cholinesterase enzymes inhibitory potentials.
ISSN:	0009-2363 1347-5223
DOI:	10.1248/cpb.53.570