Highly Enantioselective Conjugate Addition of Nitromethane to Chalcones Using Bifunctional Cinchona Organocatalysts

Cinchona alkaloid-derived chiral bifunctional thiourea organocatalysts were synthesized and applied in the Michael addition between nitromethane and chalcones with high ee and chemical yields.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Organic letters 2005-05, Vol.7 (10), p.1967-1969
Hauptverfasser:	Vakulya, Benedek, Varga, Szilárd, Csámpai, Antal, Soós, Tibor
Format:	Artikel
Sprache:	eng
Schlagworte:	Catalysis Chalcones - chemistry Cinchona - chemistry Cinchona Alkaloids - chemistry Methane - analogs & derivatives Methane - chemistry Molecular Structure Nitroparaffins - chemistry Stereoisomerism Thiourea - analogs & derivatives Thiourea - chemical synthesis Thiourea - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Cinchona alkaloid-derived chiral bifunctional thiourea organocatalysts were synthesized and applied in the Michael addition between nitromethane and chalcones with high ee and chemical yields.
ISSN:	1523-7060 1523-7052
DOI:	10.1021/ol050431s