The potential role of gap junction communication between cumulus cells and bovine oocytes during in vitro maturation

Preliminary studies in our laboratory have indicated that modulating cumulus expansion early or late during culture has a profound influence on the subsequent development of cumulus‐enclosed oocytes. Our objectives were to evaluate the effect of short term exposure to recombinant human follicle‐stim...

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Veröffentlicht in:	Molecular reproduction and development 2005-07, Vol.71 (3), p.358-367
Hauptverfasser:	Atef, Ali, François, Paradis, Christian, Vigneault, Marc-André, Sirard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences bovine oocyte Cattle Cells, Cultured cumulus cells Embryo Culture Techniques Female follicle stimulating hormone Follicle Stimulating Hormone - pharmacology Fundamental and applied biological sciences. Psychology Gap Junctions - drug effects Gap Junctions - metabolism Humans Mammalian female genital system Morphology. Physiology oocyte competence oocyte development Oocytes - cytology Oocytes - physiology Ovarian Follicle - cytology Ovarian Follicle - physiology Vertebrates: reproduction
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Beschreibung
Zusammenfassung:	Preliminary studies in our laboratory have indicated that modulating cumulus expansion early or late during culture has a profound influence on the subsequent development of cumulus‐enclosed oocytes. Our objectives were to evaluate the effect of short term exposure to recombinant human follicle‐stimulating hormone (r‐hFSH) during in vitro maturation (IVM) on cumulus expansion and developmental competence of bovine oocytes. A highly significant (P
ISSN:	1040-452X 1098-2795
DOI:	10.1002/mrd.20281