Cross-inhibition to heterologous foot-and-mouth disease virus infection induced by RNA interference targeting the conserved regions of viral genome

RNA interference (RNAi) is the process by which double-stranded RNA (dsRNA) directs sequence-specific degradation of messenger RNA in animal and plant cells. In mammalian cells, RNAi can be triggered by 21–23 nucleotide duplexes of small interfering RNA (siRNA). Strategies to inhibit RNA virus multi...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2005-05, Vol.336 (1), p.51-59
Hauptverfasser:	Liu, Mingqiu, Chen, Weizao, Ni, Zheng, Yan, Weiyao, Fei, Liang, Jiao, Ye, Zhang, Jun, Du, Qingyun, Wei, Xuefeng, Chen, Jiulian, Liu, Yumei, Zheng, Zhaoxin
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions - genetics 5' Untranslated Regions - genetics Animals Cell Line Conserved region Conserved Sequence Cricetinae Cross-inhibition FMDV foot-and-mouth disease Foot-and-mouth disease virus Foot-and-Mouth Disease Virus - genetics Foot-and-Mouth Disease Virus - physiology gene expression regulation Genome, Viral Herpesvirus 1, Suid - growth & development molecular sequence data nucleotide sequences Pseudorabies virus RNA Interference RNA interference (RNAi) RNA, Small Interfering - genetics RNA, Small Interfering - metabolism RNA, Viral - genetics small interfering RNA Transfection Viral genome Viral Proteins - genetics viral RNA Virus Replication
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