Long-Term Evolution of Lymphocytes Subsets After Induction Therapy Based on Continuous Versus Discontinuous Administration of Anti-Thymocyte Globulins in Renal-Transplant Patients

The aim of our retrospective study was to assess the long-term evolution of lymphocyte subsets after two modes of administration of anti-thymocyte globulin (ATG) after renal transplantation. Before 1993, patients (group I, n = 93) received fixed doses of RATG (1 mg/kg per day) for 8 consecutive days. Thereafter, RATG was either continued at the same dose for 15 days, in cases of delayed graft function, or was infused every other day at the same dose until the serum creatinine level became