Cytokines, Skin, and Smallpox–A New Link to an Antimicrobial Peptide
Patients with atopic dermatitis (AD) have an increased risk of infection with several viruses compared to patients with other inflammatory skin disorders such as psoriasis. In this issue of Immunity, Howell et al. (2006) find that the cytokine milieu in the skin of AD patients profoundly affects the...
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| Veröffentlicht in: | Immunity (Cambridge, Mass.) Mass.), 2006-03, Vol.24 (3), p.245-247 |
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| creator | Harrison, Jodie M. Ramshaw, Ian A. |
| description | Patients with atopic dermatitis (AD) have an increased risk of infection with several viruses compared to patients with other inflammatory skin disorders such as psoriasis. In this issue of
Immunity,
Howell et al. (2006) find that the cytokine milieu in the skin of AD patients profoundly affects the innate response to vaccinia virus (VV) by blocking production of the antimicrobial peptide LL-37. |
| doi_str_mv | 10.1016/j.immuni.2006.03.003 |
| format | Article |
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Immunity,
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Immunity,
Howell et al. 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| source | MEDLINE; Cell Press Free Archives; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Antimicrobial agents Antimicrobial Cationic Peptides - biosynthesis Cytokines Cytokines - physiology Dermatitis, Atopic - immunology Humans Immune system Immunity, Innate Infections NF-kappa B - physiology Skin - immunology Skin - virology Smallpox Smallpox Vaccine - immunology Studies Vaccinia virus - immunology Vaccinia virus - physiology Virus Replication Viruses |
| title | Cytokines, Skin, and Smallpox–A New Link to an Antimicrobial Peptide |
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