A randomized comparison of oral chloramphenicol versus ofloxacin in the treatment of uncomplicated typhoid fever in Laos

We conducted a randomized open trial of oral chloramphenicol (50 mg/kg/day in four divided doses for 14 days) versus ofloxacin (15 mg/kg/day in two divided doses for 3 days) in 50 adults with culture-confirmed uncomplicated typhoid fever in Vientiane, Laos. Patients had been ill for a median (range)...

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Veröffentlicht in:	Transactions of the Royal Society of Tropical Medicine and Hygiene 2005-06, Vol.99 (6), p.451-458
Hauptverfasser:	Phongmany, Simmaly, Phetsouvanh, Rattanaphone, Sisouphone, Siho, Darasavath, Chirapha, Vongphachane, Pankham, Rattanavong, Oudayvone, Mayxay, Mayfong, Ramsay, Andrew C., Blacksell, Stuart D., Thammavong, Chanpheng, Syhavong, Bounkong, White, Nicholas J., Newton, Paul N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adolescent Adult Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - economics Anti-Bacterial Agents - therapeutic use Bacterial diseases Bacterial diseases of the digestive system and abdomen Biological and medical sciences Chloramphenicol Chloramphenicol - administration & dosage Chloramphenicol - economics Clinical trial Female General aspects Health Care Costs Human bacterial diseases Humans Infectious diseases Laos Laos - epidemiology Male Medical sciences Microbial Sensitivity Tests Middle Aged Ofloxacin Ofloxacin - economics Ofloxacin - therapeutic use Prospective Studies Salmonella Typhi Time Factors Treatment Outcome Typhoid Typhoid Fever - drug therapy Typhoid Fever - epidemiology
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