Repaglinide in the Management of New‐Onset Diabetes Mellitus After Renal Transplantation

Repaglinide in the Management of New‐Onset Diabetes Mellitus After Renal Transplantation

The purpose of this study was to investigate the use of the short‐acting insulin secretion drug repaglinide in new‐onset diabetes mellitus (NODM) after renal transplantation. Twenty‐three Caucasian patients with NODM after renal transplantation were selected to receive repaglinide therapy and were f...

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Veröffentlicht in:American journal of transplantation 2006-04, Vol.6 (4), p.842-846
Hauptverfasser: Türk, T., Pietruck, F., Dolff, S., Kribben, A., Janssen, O. E., Mann, K., Philipp, T., Heemann, U., Witzke, O.
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Carbamates - therapeutic use
Diabetes Mellitus - drug therapy
Diabetes. Impaired glucose tolerance
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Etiopathogenesis. Screening. Investigations. Target tissue resistance
Female
Humans
Hypoglycemic Agents - therapeutic use
Kidney Transplantation
Male
Medical sciences
Middle Aged
New‐onset diabetes mellitus
Piperidines - therapeutic use
renal transplantation
repaglinide
Rosiglitazone
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the urinary system
Thiazolidinediones - therapeutic use
Treatment Outcome
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Beschreibung
Zusammenfassung:The purpose of this study was to investigate the use of the short‐acting insulin secretion drug repaglinide in new‐onset diabetes mellitus (NODM) after renal transplantation. Twenty‐three Caucasian patients with NODM after renal transplantation were selected to receive repaglinide therapy and were followed for at least 6 months. A control group treated with rosiglitazone was chosen for comparison. Successful repaglinide treatment was defined as a significant improvement of blood glucose concentrations and HbA1c
ISSN:1600-6135
1600-6143
DOI:10.1111/j.1600-6143.2006.01250.x