SUSPECTS: enabling fast and effective prioritization of positional candidates

SUSPECTS is a web-based server which combines annotation and sequence-based approaches to prioritize disease candidate genes in large regions of interest. It uses multiple lines of evidence to rank genes quickly and effectively while limiting the effect of annotation bias to significantly improve performance. Availability: SUSPECTS is freely available at Contact:euan.adie@ed.ac.uk Supplementary information: A quick-start guide in Macromedia Flash format is available at and Excel spreadsheets detailing the comparative performance of the software are included as Supplementary material.