Synthesis and Application of a Fluorous Lawesson's Reagent: Convenient Chromatography-Free Product Purification
A fluorous analogue of Lawesson's reagent for thionation of carbonyl compounds has been developed and its use demonstrated on a series of amides, esters, and ketones. The separation of the Lawesson's reagent-derived byproducts can be achieved by a simple fluorous solid-phase extraction.
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| Veröffentlicht in: | Organic letters 2006-03, Vol.8 (6), p.1093-1095 |
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| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | A fluorous analogue of Lawesson's reagent for thionation of carbonyl compounds has been developed and its use demonstrated on a series of amides, esters, and ketones. The separation of the Lawesson's reagent-derived byproducts can be achieved by a simple fluorous solid-phase extraction. |
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| ISSN: | 1523-7060 1523-7052 |
| DOI: | 10.1021/ol0529849 |