Effect of both elevated troponin-I and peripheral white blood cell count on prognosis in patients with suspected myocardial injury

Effect of both elevated troponin-I and peripheral white blood cell count on prognosis in patients with suspected myocardial injury

We found a high white blood cell count (>11,000/μl) to be of additive prognostic value to high troponin-I levels in predicting risk of recurrent nonfatal myocardial infarctions and all-cause mortality in patients who present with acute coronary syndromes and non–ST-elevation myocardial infarction...

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Veröffentlicht in:The American journal of cardiology 2005-04, Vol.95 (8), p.970-972
Hauptverfasser: Zahid, Maliha, Sonel, Ali F., Kelley, Mary E., Wall, Lauren, Whittle, Jeff, Fine, Michael J., Good, Chester B.
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Biological and medical sciences
Biomarkers - blood
Cardiology. Vascular system
Female
Heart
Humans
Injuries
Leukocyte Count
Leukocytes
Male
Medical diagnosis
Medical sciences
Myocardial Infarction - complications
Myocardial Infarction - diagnosis
Predictive Value of Tests
Prognosis
Recurrence
Risk Factors
Troponin I - blood
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Zusammenfassung:We found a high white blood cell count (>11,000/μl) to be of additive prognostic value to high troponin-I levels in predicting risk of recurrent nonfatal myocardial infarctions and all-cause mortality in patients who present with acute coronary syndromes and non–ST-elevation myocardial infarctions. A high troponin-I level or white blood cell count increased the odds ratio of an event to 2.2 (95% confidence interval 1.0 to 4.73, p = 0.05), but high values for the 2 markers increased the odds ratio to 4.5 (95% confidence interval 1.42 to 14.21, p = 0.01).
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2004.12.037