Role of the N-linked glycans of the prM and E envelope proteins in tick-borne encephalitis virus particle secretion

The tick-borne encephalitis (TBE) virus has two membrane glycoproteins (prM and E), which each has one N-linked glycan. Constructs that express prM and E proteins of TBE virus have been shown to produce virus-like particles (VLPs), which have surface properties that are similar to those of infectiou...

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Veröffentlicht in:	Vaccine 2005-04, Vol.23 (23), p.3043-3052
Hauptverfasser:	Goto, Akiko, Yoshii, Kentarou, Obara, Mayumi, Ueki, Tomotaka, Mizutani, Tetsuya, Kariwa, Hiroaki, Takashima, Ikuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Applied microbiology Biological and medical sciences Biological properties Carbohydrates Colleges & universities Encephalitis Viruses, Tick-Borne - physiology Enzymes Fundamental and applied biological sciences. Psychology Glycoproteins Glycosylation Glycosylation sites Humans Microbiology Miscellaneous Mutagenesis Mutation Plasmids Protein Folding Secretion Tick-borne encephalitis virus Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Viral Envelope Proteins - chemistry Viral Envelope Proteins - physiology Viral infections Virion - physiology Virology Viruses
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