Emergence of Vaccine-Related Pneumococcal Serotypes as a Cause of Bacteremia

Background. The heptavalent pneumococcal conjugate vaccine (PCV7) has decreased the incidence of invasive pneumococcal disease among children in the United States. In the postlicensure period, the impact of non-PCV7 serotypes against pediatric pneumococcal bacteremia is unknown. Methods. Episodes of...

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Veröffentlicht in:	Clinical infectious diseases 2006-04, Vol.42 (7), p.907-914
Hauptverfasser:	Steenhoff, Andrew P., Shah, Samir S., Ratner, Adam J., Patil, Sujata M., McGowan, Karin L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Antibiotics Articles and Commentaries Bacteremia Bacteremia - microbiology Bacteria Bacterial diseases Bacterial sepsis Biological and medical sciences Blood Child Child, Preschool Children Children & youth Confidence intervals Conjugate vaccines Data analysis Data collection Disease control Emergency departments Epidemiology Female Haemophilus influenzae Heptavalent Pneumococcal Conjugate Vaccine Hospitals Human bacterial diseases Humans Incidence Infant Infectious diseases Male Medical sciences Meningococcal Vaccines - classification Meningococcal Vaccines - immunology Moraxella catarrhalis Neisseria meningitidis Patients Pediatrics Penicillin Penicillin Resistance Pneumococcal Infections - epidemiology Pneumococcal Infections - prevention & control Pneumococcal Vaccines - classification Pneumococcal Vaccines - immunology Pneumonia Serotyping Staphylococcal infections, streptococcal infections, pneumococcal infections Streptococcus pneumoniae Streptococcus pneumoniae - classification Streptococcus pneumoniae - drug effects Vaccination Vaccines
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Zusammenfassung:	Background. The heptavalent pneumococcal conjugate vaccine (PCV7) has decreased the incidence of invasive pneumococcal disease among children in the United States. In the postlicensure period, the impact of non-PCV7 serotypes against pediatric pneumococcal bacteremia is unknown. Methods. Episodes of bacteremia due to Streptococcus pneumoniae and other respiratory pathogens (ORP), namely Neisseria meningitidis, Haemophilus influenzae, and Moraxella catarrhalis, were identified in children
ISSN:	1058-4838 1537-6591
DOI:	10.1086/500941