Myocardial asynchronism is a determinant of changes in functional mitral regurgitation severity during dynamic exercise in patients with chronic heart failure due to severe left ventricular systolic dysfunction

Aims Functional mitral regurgitation (MR) and myocardial asynchronism occur commonly in patients with dilated cardiomyopathy and affect adversely their prognosis and symptoms. The aim of this study was to evaluate the mechanisms of changes in MR severity during dynamic exercise in patients with chro...

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Veröffentlicht in:	European heart journal 2006-03, Vol.27 (6), p.679-683
Hauptverfasser:	Ennezat, Pierre V., Maréchaux, Sylvestre, Le Tourneau, Thierry, Lamblin, Nicolas, Bauters, Christophe, Van Belle, Eric, Gal, Benjamin, Kacet, Salem, Asseman, Philippe, Deklunder, Ghislaine, LeJemtel, Thierry H., de Groote, Pascal
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Blood Pressure - physiology Chronic heart failure Echocardiography, Doppler - methods Exercise - physiology Exercise echocardiology Exercise Test - methods Exercise Tolerance - physiology Female Heart Failure - diagnostic imaging Heart Failure - etiology Heart Failure - physiopathology Heart Rate - physiology Humans Male Middle Aged Mitral regurgitation Mitral Valve Insufficiency - complications Mitral Valve Insufficiency - diagnostic imaging Mitral Valve Insufficiency - physiopathology Myocardial asynchronism Severity of Illness Index Ventricular Dysfunction, Left - complications Ventricular Dysfunction, Left - diagnostic imaging Ventricular Dysfunction, Left - physiopathology
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Zusammenfassung:	Aims Functional mitral regurgitation (MR) and myocardial asynchronism occur commonly in patients with dilated cardiomyopathy and affect adversely their prognosis and symptoms. The aim of this study was to evaluate the mechanisms of changes in MR severity during dynamic exercise in patients with chronic heart failure (CHF). Methods and results Seventy patients with CHF due to left ventricular (LV) systolic dysfunction [LV ejection fraction (EF)
ISSN:	0195-668X 1522-9645
DOI:	10.1093/eurheartj/ehi682