Breeding genetically modified rodents: tips for tracking and troubleshooting reproductive performance

Infertility or reduced fertility in genetically modified mouse strains represents a serious bottleneck for planned research projects. The authors describe simple methods for troubleshooting poor reproductive performance in breeding colonies and introduce various means of assisted reproduction that m...

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Veröffentlicht in:	Lab animal 2005-04, Vol.34 (4), p.36-41
Hauptverfasser:	Murray, Kathleen A., Parker, Nancy Jean
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Husbandry Animal Models Animals Animals, Genetically Modified Biomedical and Life Sciences Breeding - methods Female Infertility - genetics Life Sciences Male Mice Reproduction - genetics Reproductive Techniques, Assisted - veterinary resource Veterinary Medicine - methods Veterinary Medicine/Veterinary Science
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Zusammenfassung:	Infertility or reduced fertility in genetically modified mouse strains represents a serious bottleneck for planned research projects. The authors describe simple methods for troubleshooting poor reproductive performance in breeding colonies and introduce various means of assisted reproduction that might be used to 'rescue' infertile lines.
ISSN:	0093-7355 1548-4475
DOI:	10.1038/laban0405-36