Serum interferon-gamma is a psoriasis severity and prognostic marker

Serum interferon-gamma is a psoriasis severity and prognostic marker

The aim of this study was to measure serum interferon-gamma (IFN-gamma) levels in participants with different types and severities of psoriasis. The study was conducted on 21 participants with psoriasis. Participants were divided into 3 groups according to disease severity: erythrodermic, severe pla...

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Veröffentlicht in:Cutis (New York, N.Y.) N.Y.), 2009-09, Vol.84 (3), p.163-168
Hauptverfasser: Abdallah, Marwa A, Abdel-Hamid, Mahmoud F, Kotb, Amr M, Mabrouk, Elham A
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Biomarkers - blood
Case-Control Studies
Enzyme-Linked Immunosorbent Assay
Female
Humans
Interferon-gamma - blood
Male
Middle Aged
Prognosis
Psoriasis - diagnosis
Psoriasis - physiopathology
Psoriasis - therapy
Remission Induction - methods
Severity of Illness Index
Treatment Outcome
Young Adult
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Zusammenfassung:The aim of this study was to measure serum interferon-gamma (IFN-gamma) levels in participants with different types and severities of psoriasis. The study was conducted on 21 participants with psoriasis. Participants were divided into 3 groups according to disease severity: erythrodermic, severe plaque, and mild to moderate plaque psoriasis. Fifteen participants received different treatment modalities for 16 weeks and were followed for an additional 12 weeks. The enzyme-linked immunosorbent assay technique was used to measure serum IFN-gamma levels in participants before treatment and compared with matched controls and participants receiving treatment. Significant differences were detected between participants and controls in mean serum IFN-gamma levels before treatment (P
ISSN:0011-4162