Therapies for Type 2 Diabetes and Coronary Artery Disease

To the Editor: In the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial (ClinicalTrials.gov number, NCT00006305) reported on by Frye and colleagues (June 11 issue), 1 patient inclusion was based on a coronary anatomy that was suitable for revascularization. Thus, the results of this study are difficult to translate into clinical practice. When evaluating a patient with chronic coronary artery disease, doctors must choose their strategy before catheterization. They may choose immediate catheterization with revascularization, if feasible (revascularization may not be suitable because of disease that is too diffuse or without relevant obstructions, as in the Trial of Invasive versus . . .