Differential viral kinetics in treated genotype 4 chronic hepatitis C patients according to ethnicity

Data concerning the efficacy of PEG‐IFNα2a plus ribavirin treatment in treatment‐naïve, genotype 4‐infected chronic hepatitis C (CHC) patients from Europe are limited. Hence the aim of this study was to investigate the viral kinetics as well as the sustained virological response (SVR) rates and thei...

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Veröffentlicht in:	Journal of viral hepatitis 2009-10, Vol.16 (10), p.738-742
Hauptverfasser:	Elefsiniotis, I. S., Pavlidis, C., Dimitroulopoulos, D., Vezali, E., Mihas, C., Mariolis-Sapsakos, T., Koutsounas, S., Paraskevas, E., Saroglou, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antiviral Agents - therapeutic use Ethnic Groups ethnicity Europe Female Genotype genotype 4 Hepacivirus - classification Hepacivirus - genetics Hepacivirus - isolation & purification hepatitis C Hepatitis C, Chronic - drug therapy Humans Interferon-alpha - therapeutic use Male Middle Aged Polyethylene Glycols - therapeutic use Predictive Value of Tests Recombinant Proteins Ribavirin - therapeutic use RNA, Viral - blood Treatment Outcome viral kinetics Viral Load
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Zusammenfassung:	Data concerning the efficacy of PEG‐IFNα2a plus ribavirin treatment in treatment‐naïve, genotype 4‐infected chronic hepatitis C (CHC) patients from Europe are limited. Hence the aim of this study was to investigate the viral kinetics as well as the sustained virological response (SVR) rates and their predictors, in these patients. One hundred and twenty‐three patients were retrospectively analysed. Early (EVR) and late virological response (LVR) was confirmed by undetectable (
ISSN:	1352-0504 1365-2893
DOI:	10.1111/j.1365-2893.2009.01134.x