In vitro extreme drug resistance assay to taxanes or platinum compounds for the prediction of clinical outcomes in epithelial ovarian cancer: a prospective cohort study

Purpose We sought to investigate the efficacy of in vitro extreme drug resistance (EDR) assay for the prediction of drug response, platinum-resistance (progression-free survival, PFS

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Veröffentlicht in:	Journal of cancer research and clinical oncology 2009-11, Vol.135 (11), p.1513-1520
Hauptverfasser:	Kim, Hee Seung, Kim, Tae Joong, Chung, Hyun Hoon, Kim, Jae Weon, Kim, Byung Gie, Park, Noh Hyun, Song, Yong Sang, Bae, Duk Soo, Kang, Soon Beom
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic agents Antineoplastic Agents - therapeutic use Biological and medical sciences Cancer Research Carboplatin - therapeutic use Cell culture Chemotherapy Cisplatin - therapeutic use Clinical outcomes Cohort Studies Drug resistance Drug Resistance, Neoplasm Female Female genital diseases Gynecology. Andrology. Obstetrics Hematology Humans Internal Medicine Medical sciences Medicine Medicine & Public Health Middle Aged Neoplasms, Glandular and Epithelial - drug therapy Neoplasms, Glandular and Epithelial - mortality Oncology Original Paper Ovarian cancer Ovarian Neoplasms - drug therapy Ovarian Neoplasms - mortality Pharmacology Pharmacology. Drug treatments Prospective Studies Taxoids - therapeutic use Tumors
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Beschreibung
Zusammenfassung:	Purpose We sought to investigate the efficacy of in vitro extreme drug resistance (EDR) assay for the prediction of drug response, platinum-resistance (progression-free survival, PFS
ISSN:	0171-5216 1432-1335
DOI:	10.1007/s00432-009-0598-0