Association of hypovitaminosis D with metabolic disturbances in polycystic ovary syndrome

ObjectivesWomen with polycystic ovary syndrome (PCOS) frequently suffer from metabolic disturbances, in particular from insulin resistance. Accumulating evidence suggests that vitamin D deficiency may contribute to the development of the metabolic syndrome (MS). Hence, the aim of our study was to in...

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Veröffentlicht in:	European journal of endocrinology 2009-10, Vol.161 (4), p.575-582
Hauptverfasser:	Wehr, E, Pilz, S, Schweighofer, N, Giuliani, A, Kopera, D, Pieber, T R, Obermayer-Pietsch, B
Format:	Artikel
Sprache:	eng
Schlagworte:	25-Hydroxyvitamin D 2 - blood Adolescent Adult Anthropometry Biological and medical sciences Blood Glucose - metabolism Body Mass Index Clinical Study Cohort Studies Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - genetics Endocrinopathies Female Fundamental and applied biological sciences. Psychology Glucose Intolerance - complications Hemodynamics - physiology Hormones - blood Humans Insulin - metabolism Lipids - blood Medical sciences Metabolic diseases Metabolic Syndrome - complications Metabolic Syndrome - metabolism Miscellaneous Other metabolic disorders Polycystic Ovary Syndrome - complications Polycystic Ovary Syndrome - metabolism Vertebrates: endocrinology Vitamin D - blood Vitamin D Deficiency - complications Vitamin D Deficiency - metabolism Young Adult
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Zusammenfassung:	ObjectivesWomen with polycystic ovary syndrome (PCOS) frequently suffer from metabolic disturbances, in particular from insulin resistance. Accumulating evidence suggests that vitamin D deficiency may contribute to the development of the metabolic syndrome (MS). Hence, the aim of our study was to investigate the association of 25(OH)D levels and the components of the MS in PCOS women.Methods25(OH)D levels were measured by means of ELISA in 206 women affected by PCOS. Metabolic, endocrine, and anthropometric measurements and oral glucose tolerance tests were performed.ResultsThe prevalence of insufficient 25(OH)D levels (
ISSN:	0804-4643 1479-683X
DOI:	10.1530/EJE-09-0432