Antidiabetic potential of Butea monosperma in rats

The antihyperglycemic activity of the ethanolic extract of Butea monosperma (BMEE) was studied in glucose-loaded and alloxan-induced diabetic rats. Single dose treatment of BMEE (200 mg/kg, p.o.) significantly improved glucose tolerance and caused reduction in blood glucose level in alloxan-induced...

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Veröffentlicht in:	Fitoterapia 2006-02, Vol.77 (2), p.86-90
Hauptverfasser:	Somani, Rahul, Kasture, Sanjay, Singhai, Abhay Kumar
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antidiabetic activity Antihyperglycemic Biological and medical sciences Blood Glucose - drug effects Butea - chemistry Butea monosperma Cholesterol - blood Cholesterol, HDL - analysis Cholesterol, HDL - drug effects Diabetes Mellitus - drug therapy Diabetes Mellitus, Experimental - drug therapy Ethanol - chemistry Female Flowers - chemistry General pharmacology Glucose Tolerance Test Hypoglycemic Agents - isolation & purification Hypoglycemic Agents - pharmacology Male Medical sciences Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phytotherapy Plant Extracts - administration & dosage Plant Extracts - pharmacology Plants, Medicinal - chemistry Rats Rats, Wistar
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Zusammenfassung:	The antihyperglycemic activity of the ethanolic extract of Butea monosperma (BMEE) was studied in glucose-loaded and alloxan-induced diabetic rats. Single dose treatment of BMEE (200 mg/kg, p.o.) significantly improved glucose tolerance and caused reduction in blood glucose level in alloxan-induced diabetic rats. Repeated oral treatment with BMEE (200 mg/kg/day) for 2 weeks significantly reduced blood glucose, serum cholesterol and improved HDL-cholesterol and albumin as compared to diabetic control group.
ISSN:	0367-326X
DOI:	10.1016/j.fitote.2005.11.003