Synthetic Approaches to the Neuraminidase Inhibitors Zanamivir (Relenza) and Oseltamivir Phosphate (Tamiflu) for the Treatment of Influenza

Synthetic Approaches to the Neuraminidase Inhibitors Zanamivir (Relenza) and Oseltamivir Phosphate (Tamiflu) for the Treatment of Influenza

Javier examines the syntheses of Relenza and Tamiflu in the treatment of influenza. Relenza aznd Tamiflu are neuraminidase inhibitors.

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Bibliographische Detailangaben
Veröffentlicht in:Chemical reviews 2009-09, Vol.109 (9), p.4398-4438
1. Verfasser: Magano, Javier
Format: Artikel
Sprache:eng
Schlagworte:
Antiviral Agents - chemical synthesis
Antiviral Agents - chemistry
Antiviral Agents - therapeutic use
Enzyme Inhibitors - chemical synthesis
Enzyme Inhibitors - chemistry
Enzyme Inhibitors - therapeutic use
Enzymes
Humans
Influenza
Influenza, Human - drug therapy
Inhibitor drugs
Neuraminidase - antagonists & inhibitors
Neuraminidase - metabolism
Oseltamivir - chemical synthesis
Oseltamivir - chemistry
Oseltamivir - therapeutic use
Pharmaceutical sciences
Zanamivir - chemical synthesis
Zanamivir - chemistry
Zanamivir - therapeutic use
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Beschreibung
Zusammenfassung:Javier examines the syntheses of Relenza and Tamiflu in the treatment of influenza. Relenza aznd Tamiflu are neuraminidase inhibitors.
ISSN:0009-2665
1520-6890
DOI:10.1021/cr800449m