Retroperitoneoscopic Versus Open Surgical Radical Nephrectomy for Large Renal Cell Carcinoma in Clinical Stage cT2 or cT3a: Quality of Life, Pain and Reconvalescence

To determine whether retroperitoneoscopic radical nephrectomy for large renal cell carcinoma in stage cT2 or cT3a is a feasible, safe and effective therapy option and if it shows any advantage regarding quality of life in comparison to open procedure. 23 patients who underwent RPNx for tumor size gr...

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Veröffentlicht in:	European urology 2006-02, Vol.49 (2), p.314-323
Hauptverfasser:	Dillenburg, Wolfgang, Poulakis, Vassilis, Skriapas, Konstantinos, de Vries, Rachelle, Ferakis, Nikolaos, Witzsch, Ulrich, Melekos, Michael, Becht, Edward
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Analysis of Variance Biological and medical sciences Body Mass Index Carcinoma, Renal Cell - pathology Carcinoma, Renal Cell - surgery Convalescence Disease-Free Survival Extraperitoneal Female Follow-Up Studies Humans Kidney cancer Kidney Neoplasms - pathology Kidney Neoplasms - surgery Kidneys Laparoscopy Large renal tumor Male Medical sciences Middle Aged Neoplasm Recurrence, Local - prevention & control Neoplasm Staging Nephrectomy Nephrectomy - methods Nephrology. Urinary tract diseases Pain Measurement Pain, Postoperative - etiology Prospective Studies Quality of Life Renal cell carcinoma Retroperitoneoscopy Time Factors Treatment Outcome Tumors of the urinary system
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Zusammenfassung:	To determine whether retroperitoneoscopic radical nephrectomy for large renal cell carcinoma in stage cT2 or cT3a is a feasible, safe and effective therapy option and if it shows any advantage regarding quality of life in comparison to open procedure. 23 patients who underwent RPNx for tumor size greater than 7cm (group 1) were matched and compared with 25 patients, who underwent ONx (group 2) for tumor with similar size characteristics. Patient and surgical data, QoL variables and complications were statistically analyzed. The median followup was 12 (range: 6–18) months for both groups. Group 1 had significantly (p
ISSN:	0302-2838 1873-7560
DOI:	10.1016/j.eururo.2005.10.021