Combing over heritable gene silencing

Recent publications suggest that certain proteins of the Polycomb group interact with DNA methyltransferases. This may connect the two systems that are known to mediate somatic inheritance of states of gene expression during development.

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Bibliographische Detailangaben
Veröffentlicht in:	Nature structural & molecular biology 2006-02, Vol.13 (2), p.100-101
Hauptverfasser:	Damelin, Marc, Ooi, Steen K T, Bestor, Timothy H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Biological Microscopy Biomedical and Life Sciences DNA - metabolism DNA Methylation DNA Modification Methylases - genetics DNA Modification Methylases - metabolism Gene Expression Regulation, Developmental Gene Silencing Life Sciences Membrane Biology Methods Methyltransferases news-and-views Physiological aspects Protein Binding Protein Structure Repressor Proteins - genetics Repressor Proteins - metabolism Structure
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Beschreibung
Zusammenfassung:	Recent publications suggest that certain proteins of the Polycomb group interact with DNA methyltransferases. This may connect the two systems that are known to mediate somatic inheritance of states of gene expression during development.
ISSN:	1545-9993 1545-9985
DOI:	10.1038/nsmb0206-100