Carbon Nanotube Delivery of the GFP Gene into Mammalian Cells
Special delivery. Amino‐functionalized multiwalled carbon nanotubes (NH2‐MWCNTs) were found to interact with negatively charged DNA and the cell membrane (see figure). Through this interaction, NH2‐MWCNTs successfully delivered the GFP (green fluorescent protein) gene into mammalian cells without an...
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| Veröffentlicht in: | Chembiochem : a European journal of chemical biology 2006-02, Vol.7 (2), p.239-242 |
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| container_end_page | 242 |
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| container_issue | 2 |
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| container_title | Chembiochem : a European journal of chemical biology |
| container_volume | 7 |
| creator | Gao, Lizeng Nie, Leng Wang, Taihong Qin, Yujun Guo, Zhixin Yang, Dongling Yan, Xiyun |
| description | Special delivery. Amino‐functionalized multiwalled carbon nanotubes (NH2‐MWCNTs) were found to interact with negatively charged DNA and the cell membrane (see figure). Through this interaction, NH2‐MWCNTs successfully delivered the GFP (green fluorescent protein) gene into mammalian cells without any cytotoxicity. The results show that NH2‐MWCNT is a novel gene carrier and has potential application in gene delivery. |
| doi_str_mv | 10.1002/cbic.200500227 |
| format | Article |
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Amino‐functionalized multiwalled carbon nanotubes (NH2‐MWCNTs) were found to interact with negatively charged DNA and the cell membrane (see figure). Through this interaction, NH2‐MWCNTs successfully delivered the GFP (green fluorescent protein) gene into mammalian cells without any cytotoxicity. 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| identifier | ISSN: 1439-4227 |
| ispartof | Chembiochem : a European journal of chemical biology, 2006-02, Vol.7 (2), p.239-242 |
| issn | 1439-4227 1439-7633 1439-4227 |
| language | eng |
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| source | MEDLINE; Access via Wiley Online Library |
| subjects | Animals Cell Line gene expression gene technology Gene Transfer Techniques green fluorescent protein Green Fluorescent Proteins - genetics Green Fluorescent Proteins - metabolism Humans Nanotechnology nanotubes Nanotubes, Carbon - chemistry Nanotubes, Carbon - ultrastructure Plasmids - genetics Plasmids - metabolism |
| title | Carbon Nanotube Delivery of the GFP Gene into Mammalian Cells |
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