Prospective cohort study comparing sequential organ failure assessment and acute physiology, age, chronic health evaluation III scoring systems for hospital mortality prediction in critically ill cirrhotic patients
Summary The aim of the study was to evaluate the usefulness of sequential organ failure assessment (SOFA) and acute physiology, age, chronic health evaluation III (APACHE III) scoring systems obtained on the first day of intensive care unit (ICU) admission in predicting hospital mortality in critica...
Gespeichert in:
| Veröffentlicht in: | International journal of clinical practice (Esher) 2006-02, Vol.60 (2), p.160-166 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 166 |
|---|---|
| container_issue | 2 |
| container_start_page | 160 |
| container_title | International journal of clinical practice (Esher) |
| container_volume | 60 |
| creator | Chen, Y-C Tian, Y-C Liu, N-J Ho, Y-P Yang, C. Chu, Y-Y Chen, P-C Fang, J-T Hsu, C-W Yang, C-W Tsai, M-H |
| description | Summary
The aim of the study was to evaluate the usefulness of sequential organ failure assessment (SOFA) and acute physiology, age, chronic health evaluation III (APACHE III) scoring systems obtained on the first day of intensive care unit (ICU) admission in predicting hospital mortality in critically ill cirrhotic patients. The study enrolled 102 cirrhotic patients consecutively admitted to ICU during a 1‐year period. Twenty‐five demographic, clinical and laboratory variables were analysed as predicators of survival. Information considered necessary to calculate the Child–Pugh, SOFA and APACHE III scores on the first day of ICU admission was also gathered. Overall hospital mortality was 68.6%. Multiple logistic regression analysis revealed that mean arterial pressure, SOFA and APACHE III scores were significantly related to prognosis. Goodness‐of‐fit was good for the SOFA and APACHE III models. Both predictive models displayed a similar degree of the best Youden index (0.68) and overall correctness (84%) of prediction. The SOFA and APACHE III models displayed good areas under the receiver–operating characteristic curve (0.917 ± 0.028 and 0.912 ± 0.029, respectively). Finally, a strong and significant positive correlation exists between SOFA and APACHE III scores for individual patients (r2 = 0.628, p |
| doi_str_mv | 10.1111/j.1742-1241.2005.00634.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_67624349</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>67624349</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3514-948e3a99c2a571af8c289708f769dda9e373efdabdd8f616a45d6dfd474879d83</originalsourceid><addsrcrecordid>eNpFUk2T1CAQTVla7of-BYuLnjYjBMjHwYNO6ezolu5ByyovVC-QCSMJEcju5I_6e2R2xl0uNPR73Y_mZRkieEHSertdkIoVOSkYWRQY8wXGJWWL3ZPs9CHxNMW0rHOOKTnJzkLYYlxwXuPn2QkpGSdFXZ1mf6-9C6OW0dxqJF3nfEQhTmpOh34Eb4YNCvrPpIdowCLnNzCgFoydvEYQgg6hTzkEg0Igp6jR2M3BOOs28wWCjb5AsvNuMBJ1GmzskL4FO0E0bkDr9RoF6Q5N5hB1H1DrPOqSJBNTuz7JAWvijEavlZH3LDMg6U00EqydkbEWSeN959INGlPhJCe8yJ61YIN-edzPsx-fPn5fXuZX31br5furXFJOWN6wWlNoGlkArwi0tSzqpsJ1W5WNUtBoWlHdKrhRqm5LUgLjqlStYhWrq0bV9Dx7c6g7epeGFKLoTZDaWhi0m4Ioq7JglDUJ-OoInG56rcToTQ9-Fv9_IgFeHwEQ0staD4M04RFXccIp4wn37oC7M1bPj3ks9s4QW7E3gNgbQOydIe6dIXZi_Xl5naLEzw98k-a9e-CD_53E0oqLn19XYkWXXzD58Etc0n8LI8Jj</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>67624349</pqid></control><display><type>article</type><title>Prospective cohort study comparing sequential organ failure assessment and acute physiology, age, chronic health evaluation III scoring systems for hospital mortality prediction in critically ill cirrhotic patients</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Chen, Y-C ; Tian, Y-C ; Liu, N-J ; Ho, Y-P ; Yang, C. ; Chu, Y-Y ; Chen, P-C ; Fang, J-T ; Hsu, C-W ; Yang, C-W ; Tsai, M-H</creator><creatorcontrib>Chen, Y-C ; Tian, Y-C ; Liu, N-J ; Ho, Y-P ; Yang, C. ; Chu, Y-Y ; Chen, P-C ; Fang, J-T ; Hsu, C-W ; Yang, C-W ; Tsai, M-H</creatorcontrib><description>Summary
The aim of the study was to evaluate the usefulness of sequential organ failure assessment (SOFA) and acute physiology, age, chronic health evaluation III (APACHE III) scoring systems obtained on the first day of intensive care unit (ICU) admission in predicting hospital mortality in critically ill cirrhotic patients. The study enrolled 102 cirrhotic patients consecutively admitted to ICU during a 1‐year period. Twenty‐five demographic, clinical and laboratory variables were analysed as predicators of survival. Information considered necessary to calculate the Child–Pugh, SOFA and APACHE III scores on the first day of ICU admission was also gathered. Overall hospital mortality was 68.6%. Multiple logistic regression analysis revealed that mean arterial pressure, SOFA and APACHE III scores were significantly related to prognosis. Goodness‐of‐fit was good for the SOFA and APACHE III models. Both predictive models displayed a similar degree of the best Youden index (0.68) and overall correctness (84%) of prediction. The SOFA and APACHE III models displayed good areas under the receiver–operating characteristic curve (0.917 ± 0.028 and 0.912 ± 0.029, respectively). Finally, a strong and significant positive correlation exists between SOFA and APACHE III scores for individual patients (r2 = 0.628, p < 0.001). This investigation confirms the grave prognosis for cirrhotic patients admitted to ICU. Both SOFA and APACHE III scores are excellent tools to predict the hospital mortality in critically ill cirrhotic patients. The overall predictive accuracy of SOFA and APACHE III is superior to that of Child–Pugh system. The role of these scoring systems in describing the dynamic aspects of clinical courses and allocating ICU resources needs to be clarified.</description><identifier>ISSN: 1368-5031</identifier><identifier>EISSN: 1742-1241</identifier><identifier>DOI: 10.1111/j.1742-1241.2005.00634.x</identifier><identifier>PMID: 16451287</identifier><language>eng</language><publisher>Oxford, UK; Malden, USA: Blackwell Science Ltd</publisher><subject>APACHE ; APACHE III ; Biological and medical sciences ; Child-Pugh ; Cirrhosis ; Critical Care ; Critical Illness ; Epidemiologic Methods ; Female ; General aspects ; Hospital Mortality ; Humans ; ICU ; Length of Stay ; Liver Cirrhosis - mortality ; Male ; Medical sciences ; Middle Aged ; Miscellaneous ; Multiple Organ Failure - mortality ; Prospective Studies ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; SOFA</subject><ispartof>International journal of clinical practice (Esher), 2006-02, Vol.60 (2), p.160-166</ispartof><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3514-948e3a99c2a571af8c289708f769dda9e373efdabdd8f616a45d6dfd474879d83</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1742-1241.2005.00634.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1742-1241.2005.00634.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17515345$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16451287$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chen, Y-C</creatorcontrib><creatorcontrib>Tian, Y-C</creatorcontrib><creatorcontrib>Liu, N-J</creatorcontrib><creatorcontrib>Ho, Y-P</creatorcontrib><creatorcontrib>Yang, C.</creatorcontrib><creatorcontrib>Chu, Y-Y</creatorcontrib><creatorcontrib>Chen, P-C</creatorcontrib><creatorcontrib>Fang, J-T</creatorcontrib><creatorcontrib>Hsu, C-W</creatorcontrib><creatorcontrib>Yang, C-W</creatorcontrib><creatorcontrib>Tsai, M-H</creatorcontrib><title>Prospective cohort study comparing sequential organ failure assessment and acute physiology, age, chronic health evaluation III scoring systems for hospital mortality prediction in critically ill cirrhotic patients</title><title>International journal of clinical practice (Esher)</title><addtitle>Int J Clin Pract</addtitle><description>Summary
The aim of the study was to evaluate the usefulness of sequential organ failure assessment (SOFA) and acute physiology, age, chronic health evaluation III (APACHE III) scoring systems obtained on the first day of intensive care unit (ICU) admission in predicting hospital mortality in critically ill cirrhotic patients. The study enrolled 102 cirrhotic patients consecutively admitted to ICU during a 1‐year period. Twenty‐five demographic, clinical and laboratory variables were analysed as predicators of survival. Information considered necessary to calculate the Child–Pugh, SOFA and APACHE III scores on the first day of ICU admission was also gathered. Overall hospital mortality was 68.6%. Multiple logistic regression analysis revealed that mean arterial pressure, SOFA and APACHE III scores were significantly related to prognosis. Goodness‐of‐fit was good for the SOFA and APACHE III models. Both predictive models displayed a similar degree of the best Youden index (0.68) and overall correctness (84%) of prediction. The SOFA and APACHE III models displayed good areas under the receiver–operating characteristic curve (0.917 ± 0.028 and 0.912 ± 0.029, respectively). Finally, a strong and significant positive correlation exists between SOFA and APACHE III scores for individual patients (r2 = 0.628, p < 0.001). This investigation confirms the grave prognosis for cirrhotic patients admitted to ICU. Both SOFA and APACHE III scores are excellent tools to predict the hospital mortality in critically ill cirrhotic patients. The overall predictive accuracy of SOFA and APACHE III is superior to that of Child–Pugh system. The role of these scoring systems in describing the dynamic aspects of clinical courses and allocating ICU resources needs to be clarified.</description><subject>APACHE</subject><subject>APACHE III</subject><subject>Biological and medical sciences</subject><subject>Child-Pugh</subject><subject>Cirrhosis</subject><subject>Critical Care</subject><subject>Critical Illness</subject><subject>Epidemiologic Methods</subject><subject>Female</subject><subject>General aspects</subject><subject>Hospital Mortality</subject><subject>Humans</subject><subject>ICU</subject><subject>Length of Stay</subject><subject>Liver Cirrhosis - mortality</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Multiple Organ Failure - mortality</subject><subject>Prospective Studies</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>SOFA</subject><issn>1368-5031</issn><issn>1742-1241</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFUk2T1CAQTVla7of-BYuLnjYjBMjHwYNO6ezolu5ByyovVC-QCSMJEcju5I_6e2R2xl0uNPR73Y_mZRkieEHSertdkIoVOSkYWRQY8wXGJWWL3ZPs9CHxNMW0rHOOKTnJzkLYYlxwXuPn2QkpGSdFXZ1mf6-9C6OW0dxqJF3nfEQhTmpOh34Eb4YNCvrPpIdowCLnNzCgFoydvEYQgg6hTzkEg0Igp6jR2M3BOOs28wWCjb5AsvNuMBJ1GmzskL4FO0E0bkDr9RoF6Q5N5hB1H1DrPOqSJBNTuz7JAWvijEavlZH3LDMg6U00EqydkbEWSeN959INGlPhJCe8yJ61YIN-edzPsx-fPn5fXuZX31br5furXFJOWN6wWlNoGlkArwi0tSzqpsJ1W5WNUtBoWlHdKrhRqm5LUgLjqlStYhWrq0bV9Dx7c6g7epeGFKLoTZDaWhi0m4Ioq7JglDUJ-OoInG56rcToTQ9-Fv9_IgFeHwEQ0staD4M04RFXccIp4wn37oC7M1bPj3ks9s4QW7E3gNgbQOydIe6dIXZi_Xl5naLEzw98k-a9e-CD_53E0oqLn19XYkWXXzD58Etc0n8LI8Jj</recordid><startdate>200602</startdate><enddate>200602</enddate><creator>Chen, Y-C</creator><creator>Tian, Y-C</creator><creator>Liu, N-J</creator><creator>Ho, Y-P</creator><creator>Yang, C.</creator><creator>Chu, Y-Y</creator><creator>Chen, P-C</creator><creator>Fang, J-T</creator><creator>Hsu, C-W</creator><creator>Yang, C-W</creator><creator>Tsai, M-H</creator><general>Blackwell Science Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200602</creationdate><title>Prospective cohort study comparing sequential organ failure assessment and acute physiology, age, chronic health evaluation III scoring systems for hospital mortality prediction in critically ill cirrhotic patients</title><author>Chen, Y-C ; Tian, Y-C ; Liu, N-J ; Ho, Y-P ; Yang, C. ; Chu, Y-Y ; Chen, P-C ; Fang, J-T ; Hsu, C-W ; Yang, C-W ; Tsai, M-H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3514-948e3a99c2a571af8c289708f769dda9e373efdabdd8f616a45d6dfd474879d83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>APACHE</topic><topic>APACHE III</topic><topic>Biological and medical sciences</topic><topic>Child-Pugh</topic><topic>Cirrhosis</topic><topic>Critical Care</topic><topic>Critical Illness</topic><topic>Epidemiologic Methods</topic><topic>Female</topic><topic>General aspects</topic><topic>Hospital Mortality</topic><topic>Humans</topic><topic>ICU</topic><topic>Length of Stay</topic><topic>Liver Cirrhosis - mortality</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Multiple Organ Failure - mortality</topic><topic>Prospective Studies</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>SOFA</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chen, Y-C</creatorcontrib><creatorcontrib>Tian, Y-C</creatorcontrib><creatorcontrib>Liu, N-J</creatorcontrib><creatorcontrib>Ho, Y-P</creatorcontrib><creatorcontrib>Yang, C.</creatorcontrib><creatorcontrib>Chu, Y-Y</creatorcontrib><creatorcontrib>Chen, P-C</creatorcontrib><creatorcontrib>Fang, J-T</creatorcontrib><creatorcontrib>Hsu, C-W</creatorcontrib><creatorcontrib>Yang, C-W</creatorcontrib><creatorcontrib>Tsai, M-H</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of clinical practice (Esher)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chen, Y-C</au><au>Tian, Y-C</au><au>Liu, N-J</au><au>Ho, Y-P</au><au>Yang, C.</au><au>Chu, Y-Y</au><au>Chen, P-C</au><au>Fang, J-T</au><au>Hsu, C-W</au><au>Yang, C-W</au><au>Tsai, M-H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prospective cohort study comparing sequential organ failure assessment and acute physiology, age, chronic health evaluation III scoring systems for hospital mortality prediction in critically ill cirrhotic patients</atitle><jtitle>International journal of clinical practice (Esher)</jtitle><addtitle>Int J Clin Pract</addtitle><date>2006-02</date><risdate>2006</risdate><volume>60</volume><issue>2</issue><spage>160</spage><epage>166</epage><pages>160-166</pages><issn>1368-5031</issn><eissn>1742-1241</eissn><abstract>Summary
The aim of the study was to evaluate the usefulness of sequential organ failure assessment (SOFA) and acute physiology, age, chronic health evaluation III (APACHE III) scoring systems obtained on the first day of intensive care unit (ICU) admission in predicting hospital mortality in critically ill cirrhotic patients. The study enrolled 102 cirrhotic patients consecutively admitted to ICU during a 1‐year period. Twenty‐five demographic, clinical and laboratory variables were analysed as predicators of survival. Information considered necessary to calculate the Child–Pugh, SOFA and APACHE III scores on the first day of ICU admission was also gathered. Overall hospital mortality was 68.6%. Multiple logistic regression analysis revealed that mean arterial pressure, SOFA and APACHE III scores were significantly related to prognosis. Goodness‐of‐fit was good for the SOFA and APACHE III models. Both predictive models displayed a similar degree of the best Youden index (0.68) and overall correctness (84%) of prediction. The SOFA and APACHE III models displayed good areas under the receiver–operating characteristic curve (0.917 ± 0.028 and 0.912 ± 0.029, respectively). Finally, a strong and significant positive correlation exists between SOFA and APACHE III scores for individual patients (r2 = 0.628, p < 0.001). This investigation confirms the grave prognosis for cirrhotic patients admitted to ICU. Both SOFA and APACHE III scores are excellent tools to predict the hospital mortality in critically ill cirrhotic patients. The overall predictive accuracy of SOFA and APACHE III is superior to that of Child–Pugh system. The role of these scoring systems in describing the dynamic aspects of clinical courses and allocating ICU resources needs to be clarified.</abstract><cop>Oxford, UK; Malden, USA</cop><pub>Blackwell Science Ltd</pub><pmid>16451287</pmid><doi>10.1111/j.1742-1241.2005.00634.x</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1368-5031 |
| ispartof | International journal of clinical practice (Esher), 2006-02, Vol.60 (2), p.160-166 |
| issn | 1368-5031 1742-1241 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_67624349 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | APACHE APACHE III Biological and medical sciences Child-Pugh Cirrhosis Critical Care Critical Illness Epidemiologic Methods Female General aspects Hospital Mortality Humans ICU Length of Stay Liver Cirrhosis - mortality Male Medical sciences Middle Aged Miscellaneous Multiple Organ Failure - mortality Prospective Studies Public health. Hygiene Public health. Hygiene-occupational medicine SOFA |
| title | Prospective cohort study comparing sequential organ failure assessment and acute physiology, age, chronic health evaluation III scoring systems for hospital mortality prediction in critically ill cirrhotic patients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T11%3A07%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Prospective%20cohort%20study%20comparing%20sequential%20organ%20failure%20assessment%20and%20acute%20physiology,%20age,%20chronic%20health%20evaluation%20III%20scoring%20systems%20for%20hospital%20mortality%20prediction%20in%20critically%20ill%20cirrhotic%20patients&rft.jtitle=International%20journal%20of%20clinical%20practice%20(Esher)&rft.au=Chen,%20Y-C&rft.date=2006-02&rft.volume=60&rft.issue=2&rft.spage=160&rft.epage=166&rft.pages=160-166&rft.issn=1368-5031&rft.eissn=1742-1241&rft_id=info:doi/10.1111/j.1742-1241.2005.00634.x&rft_dat=%3Cproquest_pubme%3E67624349%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=67624349&rft_id=info:pmid/16451287&rfr_iscdi=true |