Evaluation of gastric cancer by high-resolution three-dimensional CISS MR imaging in vitro

Abstract Objective The objective of this study was to demonstrate the usefulness of high-resolution three-dimensional (3D) constructive interference in steady-state (CISS) MR imaging for evaluating mural invasion and the morphologic features of gastric cancers in vitro. Materials and methods High-resolution 3D-CISS MR images were obtained in three surgical specimens containing three different gastric cancers. Results In early carcinoma, advanced carcinoma, and leiomyosarcoma, the depth of mural invasion at 3D-CISS MR imaging correlated well with the histopathologic stage. Conclusion High-resolution 3D-CISS MR imaging is a useful method for evaluating mural invasion and the macroscopic features of gastric cancers in vitro.