Evaluation of the vaccine potentiality of 2 strains from Leptospira interrogans serogroup Ballum

Two vacine candidate strains from Ballum serogroup were characterized and their immunogenicity and protective power were studied in hamster. The monovalent vaccine formulations obtained showed a high immunogenicity and capacity of homologous protection and, in a lesser degree, of cross protection.

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Bibliographische Detailangaben
Veröffentlicht in:	Revista cubana de medicina tropical 2005-01, Vol.57 (1), p.63-64
Hauptverfasser:	Rodríguez, Andrés González, Jiménez, Yoandra Rodríguez, Santiesteban, Niurka Batista, Abreu, Yolanda Valdés, Osenes, Juan Francisco Núñez, González, Marta González
Format:	Artikel
Sprache:	spa
Schlagworte:	Animals Bacterial Vaccines - administration & dosage Bacterial Vaccines - immunology Cricetinae Disease Models, Animal Enzyme-Linked Immunosorbent Assay Humans Leptospira interrogans - immunology Leptospira interrogans serovar canicola - immunology Leptospira interrogans serovar icterohaemorrhagiae - immunology Leptospira interrogans serovar pomona - immunology Leptospirosis - prevention & control Time Factors Weil Disease - prevention & control
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Beschreibung
Zusammenfassung:	Two vacine candidate strains from Ballum serogroup were characterized and their immunogenicity and protective power were studied in hamster. The monovalent vaccine formulations obtained showed a high immunogenicity and capacity of homologous protection and, in a lesser degree, of cross protection.
ISSN:	0375-0760