A Case of S-100-Positive Juvenile Xanthogranuloma: A Longitudinal Observation

:  We present the case of a 9‐month‐old boy with yellow‐brown papules that gradually increased in number over a period of 6 months without systemic involvement. Our case was clinicopathologically diagnosed as S‐100‐positive juvenile xanthogranuloma, and longitudinal observation revealed that strong...

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Veröffentlicht in:Pediatric dermatology 2009-07, Vol.26 (4), p.475-476
Hauptverfasser: YAMAMOTO, YOSUKE, KADOTA, MASAFUMI, NISHIMURA, YOUICHI
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Sprache:eng
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Zusammenfassung::  We present the case of a 9‐month‐old boy with yellow‐brown papules that gradually increased in number over a period of 6 months without systemic involvement. Our case was clinicopathologically diagnosed as S‐100‐positive juvenile xanthogranuloma, and longitudinal observation revealed that strong S‐100 reactivity disappeared in parallel with maturation of the lesions within 2 years after the initial diagnosis. These findings add to the complexity in cells of origin of this disorder.
ISSN:0736-8046
1525-1470
DOI:10.1111/j.1525-1470.2009.00959.x