Diagnosis of coeliac disease

Patients often have few or no gastrointestinal symptoms and can even be obese. 2 5 Conventionally diagnosis is based on the histological finding of villous atrophy in the small bowel, which recovers on a gluten-free diet. Since antibody testing has become available, anti-endomysial and anti-transglutaminase antibodies are often used as a preliminary non-invasive means to screen patients and populations. [...]in patients with IgA deficiency, IgG anti-endomysial and anti-transglutaminase antibodies need to be checked.