David Marine and the Problem of Goiter

David Marine is one of the scientists now largely remembered for the outcome of a single trial rather than for a lifetime of critical, painstaking studies--in his case of the functioning and regulation of the thyroid gland. He is remembered for his trial, with O.P Kimball as his assistant, of the effect of giving iodide to a large group of schoolgirls in Ohio from 1917 to 1922 and for showing that this greatly reduced their development of goiter. Carpenter offers a detailed discussion of Marine's discovery and contribution.