Brasilibactin A, a Cytotoxic Compound from Actinomycete Nocardia brasiliensis

A new cytotoxic compound, brasilibactin A (1), has been isolated from the actinomycete Nocardia brasiliensis IFM 0995, and the structure was elucidated on the basis of spectroscopic data and chemical means.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2005-03, Vol.68 (3), p.462-464
Hauptverfasser:	TSUDA, Masashi, YAMAKAWA, Masaaki, OKA, Seiko, TANAKA, Yasushi, HOSHINO, Yasutake, MIKAMI, Yuzuru, SATO, Ayumi, FUJIWARA, Hironori, OHIZUMI, Yasushi, KOBAYASHI, Jun'ichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents Antineoplastic Agents - chemistry Antineoplastic Agents - isolation & purification Antineoplastic Agents - pharmacology Applied microbiology Biological and medical sciences Chemotherapic agents Drug Screening Assays, Antitumor Fundamental and applied biological sciences. Psychology Humans KB Cells Leukemia L1210 Mice Microbiology Nocardia - chemistry Nocardia brasiliensis Stearic Acids - chemistry Stearic Acids - isolation & purification Stearic Acids - pharmacology
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Beschreibung
Zusammenfassung:	A new cytotoxic compound, brasilibactin A (1), has been isolated from the actinomycete Nocardia brasiliensis IFM 0995, and the structure was elucidated on the basis of spectroscopic data and chemical means.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np0496385