Comparative in vitro study on a ultra-high roughness and dense titanium coating

A new implant surface has been developed with the purpose of avoiding as much stress shielding as possible, and thus prolong the prosthesis lifespan. The aim of this study was to investigate the in vitro effect of this new ultra-high roughness and dense Titanium (Ti) surface (PG60, R a = 74 μ m ) in...

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Veröffentlicht in:	Biomaterials 2005-08, Vol.26 (24), p.4948-4955
Hauptverfasser:	Borsari, Veronica, Giavaresi, Gianluca, Fini, Milena, Torricelli, Paola, Tschon, Matilde, Chiesa, Roberto, Chiusoli, Loris, Salito, Armando, Volpert, Andreas, Giardino, Roberto
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Differentiation Cell Line Cell Proliferation Cell Survival Coated Materials, Biocompatible - chemistry Cytokines Hardness Humans Materials Testing Osseointegration - physiology Osteoblast Osteoblasts - cytology Osteoblasts - physiology Plasma spraying Surface Properties Surface roughness Titanium Titanium - analysis Titanium - chemistry
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Zusammenfassung:	A new implant surface has been developed with the purpose of avoiding as much stress shielding as possible, and thus prolong the prosthesis lifespan. The aim of this study was to investigate the in vitro effect of this new ultra-high roughness and dense Titanium (Ti) surface (PG60, R a = 74 μ m ) in comparison with medium (TI01, R a = 18 μ m ) and high (TI60, R a = 40 μ m ) roughness and open porous coatings; all the coatings were obtained by vacuum plasma spraying. MG63 osteoblast-like cells were seeded on the tested materials and polystyrene, as control, for 3 and 7 days. Cells proliferated on the material surfaces similarly to the control. Alkaline phosphatase activity had lower values for TI60 than TI01 ( p
ISSN:	0142-9612 1878-5905
DOI:	10.1016/j.biomaterials.2005.01.010