The influence of parathyroid hormone on the adult hematopoietic stem cell niche
Adult hematopoietic stem cells (HSCs) reside in the bone marrow in stable microenvironments known as the stem cell niche. One key component of the stem cell niche is cells of the osteoblastic lineage. Factors that are known to affect osteoblast activity, such as parathyroid hormone (PTH), have also...
Gespeichert in:
| Veröffentlicht in: | Current osteoporosis reports 2009-07, Vol.7 (2), p.53-57 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 57 |
|---|---|
| container_issue | 2 |
| container_start_page | 53 |
| container_title | Current osteoporosis reports |
| container_volume | 7 |
| creator | Rashidi, Narges Adams, Gregor B. |
| description | Adult hematopoietic stem cells (HSCs) reside in the bone marrow in stable microenvironments known as the stem cell niche. One key component of the stem cell niche is cells of the osteoblastic lineage. Factors that are known to affect osteoblast activity, such as parathyroid hormone (PTH), have also been shown to affect the HSCs. Treatment of mice with PTH has led to beneficial effects on the HSC pool, which have led to clinical trials of PTH treatment to enhance HSC-based therapies. |
| doi_str_mv | 10.1007/s11914-009-0010-7 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_67520550</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>67520550</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3237-2afa7fff416be4a11f45592530120a4fb07749688290e28cc33c0375ee1b69c73</originalsourceid><addsrcrecordid>eNp9kD1PwzAQhi0EoqXwA1iQJ7bAne3EzYgqvqRKXcpsue6ZpEriYidD_z2pWomN4eTT3eNX9sPYPcITAujnhFiiygDKsRAyfcGmmCuVCaHw8tzjXMsJu0lpByAEKnnNJlgWEkGUU7ZaV8TrzjcDdY548Hxvo-2rQwz1llchtqEbxx3vR85uh6bnFbW2D_tQU187nnpquaOm4V3tKrplV942ie7O54x9vb2uFx_ZcvX-uXhZZk4KqTNhvdXee4XFhpRF9CrPS5FLQAFW-Q1orcpiPhclkJg7J6UDqXMi3BSl03LGHk-5-xh-Bkq9aet0fIbtKAzJFDoXkOcwgngCXQwpRfJmH-vWxoNBMEeL5mTRjBbN0aI5hj-cw4dNS9u_G2dtIyBOQBpX3TdFswtD7MYP_5P6C4E5fCE</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>67520550</pqid></control><display><type>article</type><title>The influence of parathyroid hormone on the adult hematopoietic stem cell niche</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>Rashidi, Narges ; Adams, Gregor B.</creator><creatorcontrib>Rashidi, Narges ; Adams, Gregor B.</creatorcontrib><description>Adult hematopoietic stem cells (HSCs) reside in the bone marrow in stable microenvironments known as the stem cell niche. One key component of the stem cell niche is cells of the osteoblastic lineage. Factors that are known to affect osteoblast activity, such as parathyroid hormone (PTH), have also been shown to affect the HSCs. Treatment of mice with PTH has led to beneficial effects on the HSC pool, which have led to clinical trials of PTH treatment to enhance HSC-based therapies.</description><identifier>ISSN: 1544-1873</identifier><identifier>EISSN: 1544-2241</identifier><identifier>DOI: 10.1007/s11914-009-0010-7</identifier><identifier>PMID: 19631029</identifier><language>eng</language><publisher>New York: Current Science Inc</publisher><subject>Animals ; Cell Differentiation - physiology ; Epidemiology ; Hematopoietic Stem Cells - cytology ; Hematopoietic Stem Cells - physiology ; Humans ; Medicine ; Medicine & Public Health ; Models, Animal ; Orthopedics ; Osteoblasts - cytology ; Osteoblasts - physiology ; Parathyroid Hormone - physiology ; Signal Transduction - physiology ; Stem Cell Niche - cytology ; Stem Cell Niche - physiology ; Stem Cell Transplantation</subject><ispartof>Current osteoporosis reports, 2009-07, Vol.7 (2), p.53-57</ispartof><rights>Current Medicine Group, LLC 2009</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3237-2afa7fff416be4a11f45592530120a4fb07749688290e28cc33c0375ee1b69c73</citedby><cites>FETCH-LOGICAL-c3237-2afa7fff416be4a11f45592530120a4fb07749688290e28cc33c0375ee1b69c73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11914-009-0010-7$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11914-009-0010-7$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51298</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19631029$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rashidi, Narges</creatorcontrib><creatorcontrib>Adams, Gregor B.</creatorcontrib><title>The influence of parathyroid hormone on the adult hematopoietic stem cell niche</title><title>Current osteoporosis reports</title><addtitle>Curr Osteoporos Rep</addtitle><addtitle>Curr Osteoporos Rep</addtitle><description>Adult hematopoietic stem cells (HSCs) reside in the bone marrow in stable microenvironments known as the stem cell niche. One key component of the stem cell niche is cells of the osteoblastic lineage. Factors that are known to affect osteoblast activity, such as parathyroid hormone (PTH), have also been shown to affect the HSCs. Treatment of mice with PTH has led to beneficial effects on the HSC pool, which have led to clinical trials of PTH treatment to enhance HSC-based therapies.</description><subject>Animals</subject><subject>Cell Differentiation - physiology</subject><subject>Epidemiology</subject><subject>Hematopoietic Stem Cells - cytology</subject><subject>Hematopoietic Stem Cells - physiology</subject><subject>Humans</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Models, Animal</subject><subject>Orthopedics</subject><subject>Osteoblasts - cytology</subject><subject>Osteoblasts - physiology</subject><subject>Parathyroid Hormone - physiology</subject><subject>Signal Transduction - physiology</subject><subject>Stem Cell Niche - cytology</subject><subject>Stem Cell Niche - physiology</subject><subject>Stem Cell Transplantation</subject><issn>1544-1873</issn><issn>1544-2241</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kD1PwzAQhi0EoqXwA1iQJ7bAne3EzYgqvqRKXcpsue6ZpEriYidD_z2pWomN4eTT3eNX9sPYPcITAujnhFiiygDKsRAyfcGmmCuVCaHw8tzjXMsJu0lpByAEKnnNJlgWEkGUU7ZaV8TrzjcDdY548Hxvo-2rQwz1llchtqEbxx3vR85uh6bnFbW2D_tQU187nnpquaOm4V3tKrplV942ie7O54x9vb2uFx_ZcvX-uXhZZk4KqTNhvdXee4XFhpRF9CrPS5FLQAFW-Q1orcpiPhclkJg7J6UDqXMi3BSl03LGHk-5-xh-Bkq9aet0fIbtKAzJFDoXkOcwgngCXQwpRfJmH-vWxoNBMEeL5mTRjBbN0aI5hj-cw4dNS9u_G2dtIyBOQBpX3TdFswtD7MYP_5P6C4E5fCE</recordid><startdate>200907</startdate><enddate>200907</enddate><creator>Rashidi, Narges</creator><creator>Adams, Gregor B.</creator><general>Current Science Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200907</creationdate><title>The influence of parathyroid hormone on the adult hematopoietic stem cell niche</title><author>Rashidi, Narges ; Adams, Gregor B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3237-2afa7fff416be4a11f45592530120a4fb07749688290e28cc33c0375ee1b69c73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Animals</topic><topic>Cell Differentiation - physiology</topic><topic>Epidemiology</topic><topic>Hematopoietic Stem Cells - cytology</topic><topic>Hematopoietic Stem Cells - physiology</topic><topic>Humans</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Models, Animal</topic><topic>Orthopedics</topic><topic>Osteoblasts - cytology</topic><topic>Osteoblasts - physiology</topic><topic>Parathyroid Hormone - physiology</topic><topic>Signal Transduction - physiology</topic><topic>Stem Cell Niche - cytology</topic><topic>Stem Cell Niche - physiology</topic><topic>Stem Cell Transplantation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rashidi, Narges</creatorcontrib><creatorcontrib>Adams, Gregor B.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Current osteoporosis reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rashidi, Narges</au><au>Adams, Gregor B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The influence of parathyroid hormone on the adult hematopoietic stem cell niche</atitle><jtitle>Current osteoporosis reports</jtitle><stitle>Curr Osteoporos Rep</stitle><addtitle>Curr Osteoporos Rep</addtitle><date>2009-07</date><risdate>2009</risdate><volume>7</volume><issue>2</issue><spage>53</spage><epage>57</epage><pages>53-57</pages><issn>1544-1873</issn><eissn>1544-2241</eissn><abstract>Adult hematopoietic stem cells (HSCs) reside in the bone marrow in stable microenvironments known as the stem cell niche. One key component of the stem cell niche is cells of the osteoblastic lineage. Factors that are known to affect osteoblast activity, such as parathyroid hormone (PTH), have also been shown to affect the HSCs. Treatment of mice with PTH has led to beneficial effects on the HSC pool, which have led to clinical trials of PTH treatment to enhance HSC-based therapies.</abstract><cop>New York</cop><pub>Current Science Inc</pub><pmid>19631029</pmid><doi>10.1007/s11914-009-0010-7</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1544-1873 |
| ispartof | Current osteoporosis reports, 2009-07, Vol.7 (2), p.53-57 |
| issn | 1544-1873 1544-2241 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_67520550 |
| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Animals Cell Differentiation - physiology Epidemiology Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - physiology Humans Medicine Medicine & Public Health Models, Animal Orthopedics Osteoblasts - cytology Osteoblasts - physiology Parathyroid Hormone - physiology Signal Transduction - physiology Stem Cell Niche - cytology Stem Cell Niche - physiology Stem Cell Transplantation |
| title | The influence of parathyroid hormone on the adult hematopoietic stem cell niche |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T07%3A56%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20influence%20of%20parathyroid%20hormone%20on%20the%20adult%20hematopoietic%20stem%20cell%20niche&rft.jtitle=Current%20osteoporosis%20reports&rft.au=Rashidi,%20Narges&rft.date=2009-07&rft.volume=7&rft.issue=2&rft.spage=53&rft.epage=57&rft.pages=53-57&rft.issn=1544-1873&rft.eissn=1544-2241&rft_id=info:doi/10.1007/s11914-009-0010-7&rft_dat=%3Cproquest_cross%3E67520550%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=67520550&rft_id=info:pmid/19631029&rfr_iscdi=true |