A furanocoumarin and polymethoxylated flavonoids from the Yucatec Mayan plant Casimiroa tetrameria

Eight polymethoxylated flavonoids and a furanocoumarin were isolated from the Yucatec Mayan medicinal plant Casimiroa tetrameria. Structures were assigned on the basis of 1 and 2D NMR spectral studies. As part of an ongoing study of the medicinal plants of the Yucatec Maya, Casimiroa tetrameria was investigated for its phytochemistry. From an ethyl acetate partition of an ethanol extract of the leaves, eight flavonoids and a furanocoumarin were isolated and characterised as 5,6,2′,3′,5′,6′-hexamethoxyflavone, 5,6,2′,3′,6′-pentamethoxyflavone and 5-methoxy-8-(3″-hydroxymethyl-but-2″-enyloxy)-psoralen using a combination of 1H, 13C NMR and NOESY spectroscopy.