Rapid Differential Diagnosis of Graves' Disease and Painless Thyroiditis Using Total T3/T4 Ratio, TSH, and Total Alkaline Phosphatase Activity

Rapid Differential Diagnosis of Graves' Disease and Painless Thyroiditis Using Total T3/T4 Ratio, TSH, and Total Alkaline Phosphatase Activity

When thyrotoxic patients are first seen in an outpatient clinic, it is important to make a differential diagnosis of Graves' disease (GD) and painless thyroiditis (PT). Using the three parameters of total T3/T4 ratio, TSH and T-ALP activity, all of which can be obtained within one hour in our h...

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Veröffentlicht in:ENDOCRINE JOURNAL 2005, Vol.52(1), pp.29-36
Hauptverfasser: YANAGISAWA, Tetsuo, SATO, Kanji, KATO, Yoshiyuki, SHIMIZU, Satoru, TAKANO, Kazue
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Alkaline phosphatase
Alkaline Phosphatase - blood
Female
Graves Disease - blood
Graves Disease - diagnosis
Graves' disease
Humans
Likelihood Functions
Male
Middle Aged
Pain - physiopathology
Painless thyroiditis
Subacute thyroiditis
Thyroiditis - blood
Thyroiditis - diagnosis
Thyroiditis - physiopathology
Thyrotropin - blood
Thyroxine - blood
Triiodothyronine - blood
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Zusammenfassung:When thyrotoxic patients are first seen in an outpatient clinic, it is important to make a differential diagnosis of Graves' disease (GD) and painless thyroiditis (PT). Using the three parameters of total T3/T4 ratio, TSH and T-ALP activity, all of which can be obtained within one hour in our hospital, 173 untreated patients with thyrotoxicosis were evaluated for the ratio of each parameter. For GD vs. PT, total T3/T4 (ng/μg) ratio (>20), TSH (
ISSN:0918-8959
1348-4540
DOI:10.1507/endocrj.52.29