Multifocal cutaneous mucormycosis complicating polymicrobial wound infections in a tsunami survivor from Sri Lanka

A man injured in the tsunami of Dec 26, 2004, returned to Sydney for management of his soft-tissue injuries. Despite broad-spectrum antibiotics, surgical wound debridement, and vigilant wound care, his condition worsened. Muscle and fat necrosis developed in a previously debrided thigh wound, and ne...

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Veröffentlicht in:The Lancet (British edition) 2005-03, Vol.365 (9462), p.876-878
Hauptverfasser: Andresen, David, Donaldson, Annabelle, Choo, Lennart, Knox, Adrian, Klaassen, Michael, Ursic, Caesar, Vonthethoff, Leon, Krilis, Steven, Konecny, Pamela
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Sprache:eng
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Zusammenfassung:A man injured in the tsunami of Dec 26, 2004, returned to Sydney for management of his soft-tissue injuries. Despite broad-spectrum antibiotics, surgical wound debridement, and vigilant wound care, his condition worsened. Muscle and fat necrosis developed in a previously debrided thigh wound, and necrotising lesions arose from previous abrasions. Histological analysis showed mucormycosis in three non-contiguous sites, and Apophysomyces elegans was isolated from excised wound tissue. Wound infections, both bacterial and fungal, will undoubtedly add to the morbidity and mortality already recorded in tsunami-affected areas. Other causes of cutaneous mucormycosis might develop in survivors, but this disease can be difficult to diagnose and even harder to treat, particularly in those remaining in affected regions. Published online January 27, 2005 http://image.thelancet.com/extras/05let1078web.pdf
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(05)71046-1