Alcohol consumption and 5-year onset of chronic kidney disease: the AusDiab study

Background. Excessive alcohol consumption is a risk factor for hypertension and stroke; however, evidence for an association with chronic kidney disease is conflicting. Methods. A total of 6259 adults ≥25 years of age, without a history of alcohol dependence, participating in baseline (1999–2000) and follow-up (2004–2005) phases of an Australian population-representative study (AusDiab) were the subject of this analysis. Alcohol consumption status and volume/frequency were collected by standardized interviewer administered questionnaires and self-administered food frequency questionnaires. The outcomes were as follows: (i) 5-year decline in estimated glomerular filtration rate (eGFR) ≥10%, with baseline eGFR ≥ 60 and final eGFR