Mutation of the prothrombin gene and thrombotic events in patients with polycythemia vera or essential thrombocythemia: a cohort study

The association between a prothrombin mutation and the risk of thrombosis was analyzed in 214 patients with polycythemia vera or essential thrombocythemia. The rate for venous thrombotic events was 14.7/100 patient-years in patients with the prothrombin mutation compared to 0.8 in patients without t...

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Veröffentlicht in:Haematologica (Roma) 2005-03, Vol.90 (3), p.408-410
Hauptverfasser: Gisslinger, H, Mullner, M, Pabinger, I, Heis-Vahidi-Fard, N, Gisslinger, B, Brichta, A, Bachleitner-Hofmann, T, Mannhalter, C
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container_title Haematologica (Roma)
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creator Gisslinger, H
Mullner, M
Pabinger, I
Heis-Vahidi-Fard, N
Gisslinger, B
Brichta, A
Bachleitner-Hofmann, T
Mannhalter, C
description The association between a prothrombin mutation and the risk of thrombosis was analyzed in 214 patients with polycythemia vera or essential thrombocythemia. The rate for venous thrombotic events was 14.7/100 patient-years in patients with the prothrombin mutation compared to 0.8 in patients without the mutation (rate ratio 17.5).
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source MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals
subjects Aged
Cohort Studies
Female
Humans
Male
Middle Aged
Mutation
Polycythemia Vera - complications
Polycythemia Vera - epidemiology
Polycythemia Vera - genetics
Prothrombin - genetics
Thrombocythemia, Essential - complications
Thrombocythemia, Essential - epidemiology
Thrombocythemia, Essential - genetics
Thrombosis - etiology
Thrombosis - genetics
title Mutation of the prothrombin gene and thrombotic events in patients with polycythemia vera or essential thrombocythemia: a cohort study
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