Cranial MRI in Acute Hyperammonemic Encephalopathy

Cranial magnetic resonance imaging was performed in three cases of acute hyperammonemic encephalopathy with three diverse etiologies: infantile citrullinemia, acute hepatic encephalopathy, and proximal urea cycle disorder. All three patients exhibited diffuse extensive cortical signal changes and sw...

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Veröffentlicht in:	Pediatric neurology 2009-08, Vol.41 (2), p.139-142
Hauptverfasser:	Bindu, Parayil S., DM, Sinha, Sanjib, DM, Taly, Arun B., DM, Christopher, Rita, MD, Kovoor, Jerry M.E., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Brain - pathology Brain Diseases, Metabolic - diagnosis Brain Diseases, Metabolic - etiology Brain Diseases, Metabolic - pathology Child, Preschool Citrullinemia - complications Diagnosis, Differential Diffusion Magnetic Resonance Imaging Early Diagnosis Female Hepatic Encephalopathy - diagnosis Hepatic Encephalopathy - pathology Humans Hyperammonemia - diagnosis Hyperammonemia - etiology Hyperammonemia - pathology Infant Investigative techniques, diagnostic techniques (general aspects) Magnetic Resonance Imaging Male Medical sciences Nervous system Neurology Pediatrics Radiodiagnosis. Nmr imagery. Nmr spectrometry
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Zusammenfassung:	Cranial magnetic resonance imaging was performed in three cases of acute hyperammonemic encephalopathy with three diverse etiologies: infantile citrullinemia, acute hepatic encephalopathy, and proximal urea cycle disorder. All three patients exhibited diffuse extensive cortical signal changes and swelling. Neurologic outcome was poor in all three cases. Knowledge of the magnetic resonance imaging findings of hyperammonemic encephalopathy may help in early diagnosis and treatment and could influence the neurologic outcome.
ISSN:	0887-8994 1873-5150
DOI:	10.1016/j.pediatrneurol.2009.02.012