Multistep One-Pot Wittig/Nazarov Reaction for Construction of Cyclopentenone with Diazo Compounds and Acid Chlorides

A facile multistep one-pot synthesis of single or fused cyclopentenones has been developed. The sequence involves a transition metal-catalyzed ylide formation/Wittig Olefination/Nazarov Cyclization.

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Veröffentlicht in:Organic letters 2009-07, Vol.11 (14), p.3048-3051
Hauptverfasser: Cao, Peng, Sun, Xiu-Li, Zhu, Ben-Hu, Shen, Qi, Xie, Zuowei, Tang, Yong
Format: Artikel
Sprache:eng
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Zusammenfassung:A facile multistep one-pot synthesis of single or fused cyclopentenones has been developed. The sequence involves a transition metal-catalyzed ylide formation/Wittig Olefination/Nazarov Cyclization.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol901086f