Resveratrol derivatives from the roots of Vitis thunbergii

Investigating the constituents of the roots of Vitis thunbergii led to the isolation of four new resveratrol derivatives, vitisinols A-D (1-4), together with (+)-epsilon-viniferin, (-)-viniferal, ampelopsin C, miyabenol A, (+)-vitisin A, and (+)-vitisin C. The structures of these 10 compounds were e...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2005-02, Vol.68 (2), p.217-220
Hauptverfasser:	Huang, Y.L, Tsai, W.J, Shen, C.C, Chen, C.C
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants - chemistry Antioxidants - isolation & purification Antioxidants - pharmacology Benzofurans - chemistry Benzofurans - isolation & purification Benzofurans - pharmacology Biflavonoids - chemistry Biflavonoids - isolation & purification Biflavonoids - pharmacology Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Catechin - chemistry Catechin - isolation & purification Catechin - pharmacology chemical structure General pharmacology Medical sciences medicinal plants Molecular Structure Nuclear Magnetic Resonance, Biomolecular Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phenols - chemistry Phenols - isolation & purification Phenols - pharmacology phytochemicals plant extracts Plant Roots - chemistry Plants, Medicinal - chemistry Platelet Aggregation Inhibitors - chemistry Platelet Aggregation Inhibitors - isolation & purification Platelet Aggregation Inhibitors - pharmacology Proanthocyanidins - chemistry Proanthocyanidins - isolation & purification Proanthocyanidins - pharmacology resveratrol roots spectral analysis stereochemistry Stilbenes - chemistry Stilbenes - isolation & purification Stilbenes - pharmacology Taiwan Vitis Vitis - chemistry Vitis ficifolia Vitis thunbergii
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Beschreibung
Zusammenfassung:	Investigating the constituents of the roots of Vitis thunbergii led to the isolation of four new resveratrol derivatives, vitisinols A-D (1-4), together with (+)-epsilon-viniferin, (-)-viniferal, ampelopsin C, miyabenol A, (+)-vitisin A, and (+)-vitisin C. The structures of these 10 compounds were established by spectroscopic (NMR and MS) analyses. All of the isolated compounds, except 1, were tested for their antiplatelet and antioxidative activities.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np049686p