Using Azobenzene-Embedded Self-Assembled Monolayers To Photochemically Control Cell Adhesion Reversibly

A celling point: A mixed self-assembled monolayer comprising two types of alkanethiols--one containing an azobenzene unit terminated with a peptide, the other containing a hexa(ethylene glycol) group that resists nonspecific cell adhesion--enables cell adhesion to be modulated photochemically. The r...

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Veröffentlicht in:Angewandte Chemie (International ed.) 2009-01, Vol.48 (24), p.4406-4408
Hauptverfasser: Liu, Dingbin, Xie, Yunyan, Shao, Huawu, Jiang, Xingyu
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Sprache:eng
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Zusammenfassung:A celling point: A mixed self-assembled monolayer comprising two types of alkanethiols--one containing an azobenzene unit terminated with a peptide, the other containing a hexa(ethylene glycol) group that resists nonspecific cell adhesion--enables cell adhesion to be modulated photochemically. The reversible conversion of the azobenzene moiety between E and Z configurations allows the surface to either support or resist cell adhesion.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200901130