Osteoporosis Treatment and Progression of Aortic Stenosis

A decrease in bone mineral density has been reported to be associated with increased progression of aortic stenosis (AS). We hypothesized that osteoporosis treatment (OT) is associated with decreased progression of AS. We performed an observational study of patients with AS from our echocardiographi...

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Veröffentlicht in:The American journal of cardiology 2009-07, Vol.104 (1), p.122-124
Hauptverfasser: Skolnick, Adam H., MD, Osranek, Martin, MD, MSc, Formica, Philip, MD, Kronzon, Itzhak, MD
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Sprache:eng
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Zusammenfassung:A decrease in bone mineral density has been reported to be associated with increased progression of aortic stenosis (AS). We hypothesized that osteoporosis treatment (OT) is associated with decreased progression of AS. We performed an observational study of patients with AS from our echocardiographic database comparing 18 patients on OT (bisphosphonates, calcitonin, or estrogen receptor modulators) with 37 patients not on OT. All patients had serial echocardiograms. Patients with mitral stenosis, aortic valve replacement, renal failure, calcium disorders, or left ventricular ejection fraction
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2009.02.051